Our projects
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frenCH reseArch Network aGaINst Glioblastoma
Objectives
The CHANGING project aims to better understand the biological and clinical importance of GAMC to develop new clinically relevant biomarkers and innovative therapeutic strategies. To achieve this project, CHANGING will create five work packages (WP):
(i) WP1 will build the national, virtual, interoperable, and multimodal database/biobank on glioblastoma, whose resources will be used by other WPs/projects;
(ii) WP2 will study the biological value of GAMC through multi-omics studies on single cells;
(iii)…
Project period:
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Main investigator
Ahmed Id Baih, AP-HP
SESSTIM member(s) of the project
Sponsors
Institut National du Cancer (INCa)
Research topics
Development of Patient Partnership in the PACA Region
Objectives
This project revolves around two main objectives:
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Characterize the regional landscape and analyze the underlying processes of the ARS initiative (mapping existing patient partnership initiatives across university hospitals, comprehensive cancer centers, and primary care settings; analyzing implementation pathways, barriers, facilitators, and service-user engagement; co-designing operational tools).
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Project period:
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Main investigator
Mathieu Bourhis
SESSTIM member(s) of the project
Sponsors
Agence Régionale de Santé Provence-Alpes-Côte d'Azur (ARS PACA)
Research topics
Health check-up in migrants enrolling in M-FUND health access scheme
Objectives
Explore the feasibility and pilot the implementation of a health check-up at enrolment of new M-FUND members, and document implications for covering healthcare.
Project period:
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Main investigator
Jordi Landier, Emilie Mosnier (SESSTIM/PIMIT), Nicolas Durier
SESSTIM member(s) of the project
Sponsors
FEF, ISSPAM
Research topics
Understanding the drivers and barriers to participation in the FILOmene cohort: a qualitative study – FILOQUALI
Objectives
The objectives of the FILOQUALI project are as follows :
1) To analyse social variations in discourse regarding the conditions for participating in a cohort such as FILOMENE, and more broadly regarding trust in scientific research, concerns about environmental health risks, and trust in the processing of personal data by a third party such as Inserm
2) Identify the specific drivers (benefits that could be offered to future participants) and barriers (methods of biological data collection, digital access, etc.) to…
Project period:
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Main investigator
Agnès Dumas
SESSTIM member(s) of the project
Non-SESSTIM member(s) of the project
Camille Davisse-Paturet, Institut Pierre Louis d’Épidémiologie et de Santé publique, dans l'équipe ESSMA Épidémiologie Sociale, Santé Mentale et Addictions.
Sponsors
INSERM
Research topics
The ethics of early risk and cancer detection: a Study on Experiences of Active Surveillance in Oncology
Objectives
SEASOn aims to produce an ethical framework with concerned stakeholders addressing high-stakes public health issues surrounding the fast-paced development of early risk and cancer detection.
Project period:
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Main investigator
Julia Tinland
SESSTIM member(s) of the project
Sponsors
HORIZON-MSCA-2024-PF-01
Research topics
Retention, Healthcare Access, and Disease Burden among Migrants in Thailand: an Analysis of M-FUND (the Migrant Fund) – Community-based Health Access Scheme Database
Objectives
This study aims to document migrant healthcare utilization and health seeking behaviour when provided access to care through M-FUND. The analysis of M-FUND database will provide a detailed description of participants (M-FUND members) profiles, document their retention in the M-FUND, map their healthcare access patterns, and evaluate disease burden from heathcare-provider reported data regarding medical events covered by M-FUND.
Project period:
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Main investigator
Jordi Landier, Emilie Mosnier (SESSTIM/PIMIT), Nicolas Durier (DLP), Nyan Linn (DLP)
SESSTIM member(s) of the project
Sponsors
FEF, ISSPAM
(Re)thinking Information and Consent in Pediatric Oncology with a participatory approach
Objectives
• To update and analyze, from a transdisciplinary perspective, the issues surrounding information and consent procedures related to the use of data and biological samples—whether or not they involve genomics—in pediatric oncology, in order to clarify the information processes that precede consent in research and clinical care.
• To conduct a participatory evaluation of existing information and decision-making tools, in collaboration with stakeholders (former patients, parents, and healthcare…
Project period:
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Main investigator
Sandrine de Montgolfier
SESSTIM member(s) of the project
Sponsors
The French National Cancer Institute (INCa)
Research topics
Validated non-invasive liquid biopsy tests for cancer PREDIction in LYNCH Syndrome
Objectives
This project revolves around two objectives:
- To assess several promising technologies based on non-invasive liquid biopsies, using an innovative clinical trial protocol.
- To detect at an early stage the three most common types of cancer associated with Lynch syndrome.
Project period:
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Main investigator
Mev Dominguez ; Oslo University Hospital
SESSTIM member(s) of the project
Sponsors
European Commission Horizon Europe Mission on Cancer
Research topics
Adjuvant endocrine therapy in non-metastatic breast cancer: decisional issues surrounding treatment extension and strategies to improve follow-up and support for women
Objectives
The primary objective is to describe the perceptions and factors influencing adherence to the proposal to extend adjuvant endocrine therapy (AET) among women with hormone-sensitive breast cancer, and to explore strategies to strengthen the follow-up and support of these women.
The secondary objectives are to:
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Describe the experience of AET among women treated for more than 5 years, and the factors influencing the decision to continue…
Project period:
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Main investigator
Géraldine Cazorla, Doctoral fellow
SESSTIM member(s) of the project
Non-SESSTIM member(s) of the project
Lorène Seguin, oncologist and Magali Provansal, oncologists, Paoli-Calmettes Institute, Murielle Sevenne, patient research partner
Sponsors
The League Against Cancer (Ligue contre le cancer, LCC), as part of the LCC-labelled teams 2024–2026
Research topics
HEPAT-B : a French national prospective cohort of patients with chronic hepatitis B virus (HBV) infection
Objectives
Main objective: To document the clinical and biological events and experiences of patients with chronic infection or hepatitis B, with or without long-term treatment.
Social sciences objectives:
- To document the experiences and difficulties encountered by people living with chronic hepatitis B, from screening to care, in order to better meet their needs and provide recommendations for adapting health service activities to this population,
- Identify psychosocial (quality of life, mental health), behavioral and socioeconomic factors associated with liver disease…
Project period:
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Main investigator
CARRAT Fabrice (UMR-S 1136 CLEPIVIR Institut Pierre Louis Epidémiologie et Santé Publique)
SESSTIM member(s) of the project
Non-SESSTIM member(s) of the project
CARRAT Fabrice (UMR-S 1136 CLEPIVIR Institut Pierre Louis Epidémiologie et Santé Publique); BOURLIÈRE Marc (Hépato-Gastroentérologie Hôpital Saint Joseph); PARLATI Lucia (Pôle d'Hépato-gastroentérologie Hôpital Cochin); ZOULIM Fabien (Inserm U1052 Centre de Recherche en Cancérologie de Lyon (CRCL) Physiopathologie des hépatites B et C et nouvelles stratégies antivirales Centre Léon Bérard); MARADAN Gwenaelle Observatoire Régional de la Santé Provence-Alpes-Côte d’Azur (ORS PACA)
Sponsors
ANRS-MIE
Research topics
HBV unIversal vs Point-Of-Care-based Antiviral treatMent to Prevent mother-to child transmission: a multi-country cluster-randomized non-inferiority trial (social sciences component)
Objectives
The main objective is to evaluate whether a targeted strategy using an innovative point-of-care test in HBV-infected pregnant women followed up at the primary health center level is non-inferior to a universal approach, where all HBV-infected women receive tenovofir (TDF) prophylaxis, in terms of retention in care and reduction in maternal HBV DNA levels at the time of delivery.
The social science component aims to:
- Compare the acceptability, appropriateness, uptake and feasibility of the two strategies.
- Assess women's HBV knowledge, empowerment and health skills…
Project period:
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Main investigator
Yusuke Shimakawa (Institut Pasteur Paris), Didier Ekouevi (université Lomé), Olivier Ségéral (hopitaux universitaires de Genêve)
SESSTIM member(s) of the project
Non-SESSTIM member(s) of the project
Kim RATTANA (National Maternal and Child Health Center, Cambodia); GUINGANE Nanelin Alice (Centre de Recherche Internationale pour la Santé (CRIS, Burkina Faso)); PHAM Minh Khue (Faculty of Public Health Haiphong University of Medicine and Pharmacy Vietnam); Raoul MOH (PACCI, Côte d'Ivoire); TZEUTON Christian (Faculty of Medicine and Pharmaceutical Sciences of Douala University of Douala, Cameroun); Gwenaëlle MARADAN (ORS-PACA)
Sponsors
ANRS-MIE
Améliorer le parcours de soin en cancérologie : une recherche interventionnelle pour systématiser l’accès aux soins oncologiques de supports (SOS) et aux patients-partenaires (PP)
Objectives
Les objectifs de cette recherche sont de :
1. Analyser la mise en œuvre de ce parcours de SOS spécifique ;
2. Identifier les conditions d’implication des PP dans le parcours de soin et dans l’équipe médicale ;
3. Décrire et mesurer les effets de l’intervention ;
4. Identifier les conditions de la pérennisation et de la transférabilité du projet ;
5. Décrire et analyser la mise en œuvre effective de la recherche participative.
Project period:
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Main investigator
Sandrine de Montgolfier, Co-PI: Séverine Carillon
SESSTIM member(s) of the project
Sandrine DE MONTGOLFIER, Séverine CARILLON, Marie-Alice KONG-HAP
Non-SESSTIM member(s) of the project
Marguerite Tyran (Institut Paoli Calmette - IPC)
Maguy Del Rio, Claire Lemanski (Institut du cancer de Montpellier - ICM)
Silvia Rossi (INSPIIRE)
Sponsors
Institut national du Cancer (INCa)
