CaLIPSo

The main objective of the TRI-MOM project is to strengthen the prevention of MTCT of HIV, syphilis and HBV among pregnant women in Burkina Faso and The Gambia, based on an integrated, horizontal and coordinated triple elimination strategy for MTCT as recommended by the WHO and the health authorities of the two countries involved in the project.  
The specific objectives are to: 
1/ Strengthen the provision of HBV screening combined with HIV and syphilis screening for pregnant women in maternal and child health services in Burkina Faso and The Gambia. 

This project on cancers under surveillance, their diagnosis, the terminology surrounding them and the experiences of patients-in-waiting is structured in 3 axes: 

(1) Better understanding the needs, experiences and expectations of people diagnosed with thyroid and prostate cancer under active surveillance for at least 1 year in the PACA region. 

This study aims to improve knowledge regarding health mediation practices. It focuses on access to the prevention of colorectal, breast and cervical cancers in socio-economically vulnerable populations with a low participation rate in national organized screening campaigns and vaccination.

The specific objectives of the study are:

1) Describe, compare and analyze the two interventions making up the “13 in health” project: SEPT and COREHSAN.

Main objective: To document the clinical and biological events and experiences of patients with chronic infection or hepatitis B, with or without long-term treatment. 
Social sciences objectives: 
- To document the experiences and difficulties encountered by people living with chronic hepatitis B, from screening to care, in order to better meet their needs and provide recommendations for adapting health service activities to this population,

The main objective is to evaluate whether a targeted strategy using an innovative point-of-care test in HBV-infected pregnant women followed up at the primary health center level is non-inferior to a universal approach, where all HBV-infected women receive tenovofir (TDF) prophylaxis, in terms of retention in care and reduction in maternal HBV DNA levels at the time of delivery. 
The social science component aims to: 
- Compare the acceptability, appropriateness, uptake and feasibility of the two strategies.

Primary Objective:To model the progression of individuals at risk of developing cirrhosis due to harmful alcohol use, focusing on effectiveness and cost-effectiveness. The aim is to predict the impact of various interventions on the incidence of cirrhosis and hepatocellular carcinoma (HCC) in France.
Secondary Objective:To evaluate the impact of healthcare interventions, such as early detection of HCC and therapeutic management, on the survival of patients with alcohol-related cirrhosis in France.