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3rd Corsican Summer School on Modern Methods in Biostatistics and Epidemiology 2022

Statistical methods and recent advances in statistical methods
for excess risk analysis


July Monday 04th to Friday 08th, 2022

Built on the success of the previous editions of the Corsican Summer School (2017, 2019), organized by Professor Roch Giorgi and by the Challenges in the Estimation of Net SURvival (CENSUR) working survival Group, the fourth edition will take place from July 04th to 08th, 2022, in Corte (Corsica, France).

As part of the HEAR+STAT series of courses, this intensive course cover the field of net survival and excess mortality, investigating both theoretical and application aspects using R software. The Summer School is aimed at biostatisticians, statisticians, epidemiologists; researchers and students; those working in a registry of cancer, of chronic disease or in any other field relevant to these methodologies and applications.

The city of Corte (Corsica, France) will host this international course. At the foot of the Corsican mountains, with beautiful natural swimming pool carved in rocks, also close to the sea, Corte has a pleasant and friendly atmosphere which has always been much appreciated by participants. This environment makes it an excellent meeting point for researchers to exchange theory, methods and applications of statistical methods and advanced methods in health research and practice.

  • Theme of the course and objectives

    Net survival, the survival related to excess mortality hazard, is a measure of disease survival and can be interpreted as the survival that would be observed in a hypothetical situation where all the risks of dying from other causes than the disease of interest have been removed. The statistical methods for excess risk analysis have been developed to analyse data from population-based cancer registries, providing useful indicators to study socioeconomic inequalities in cancer survival, in the evaluation of health policies, and for public health decision making.

    The complexity of the research questions and of the data, the necessity to have more adequate tolls, to improve the quality and the comparability of cancer survival data, and to promote methodological transfers in areas of emerging interest constitute some methodological challenges.

    The course will focus on:

    • the main statistical methods and the more recent advances in statistical methods for excess risk analysis;
    • the transfer of methods for net survival estimations to some other specific applications (clinical research, occupational epidemiology).

    The course will be taught by international researchers (France, United-Kingdom, and Slovenia) highly skilled in biostatistics, methodology, and epidemiology, from different research departments and implied in French (FRANCIM) and European (EUROCARE) networks of cancer registries.

    The main objectives of the course are:

    • to disseminate the concepts, methods and the more recent statistical tools to analyse net survival and excess mortality;
    • to offer an informal and user-friendly setting of scientific exchanges in order to improve knowledge and practical skills to estimate, model, program, analyse and interpret results of excess risk analysis.

    Programme

    The scientific programme has been designed to meet the double objective of acquiring knowledge and skills in order to estimate, model, program using R software, analyse and interpret results of excess risk analysis.

    Themes of the course:

    • Goals, epistemological aspects
    • Indicators-Interpretation
    • Non-parametric estimators of net survival
    • Parametric models for excess mortality
    • Flexible parametric models for excess mortality
    • Handling missing data
    • Diagnostic tools
    • Frailty models
    • Multiple events analysis
    • Handling expected rates tables (without, with missing information) and extensions to other fields: clinical research, epidemiology of occupational health
    Scientific programme of the course

    Faculty

    An international faculty composed of international researchers (France, United-Kingdom, and Slovenia) highly skilled in biostatistics, methodology, and epidemiology, from different research departments and implied in French (FRANCIM) and European (EUROCARE) networks of cancer registries.


    Aurélien Belot

    Inequalities in Cancer Outcomes Network, London School of Hygiene & Tropical Medicine, London, United-Kingdom

    Guy Hédelin

    Institut National de Recherche et de Sécurité,
    Vandoeuvre-lès-Nancy, France


    Hadrien Charvat

    National Cancer Center, Tokyo, Japan

    Valérie Jooste

    Registre Bourguignon des Cancers Digestifs FRANCIM,
    CHU de Dijon, INSERM 1231, Dijon, France


    Emmanuelle Dantony

    Hospices Civils de Lyon-UMR 5558, Université de Lyon, CNRS, France

    Edmund Njeru Njagi

    Inequalities in Cancer Outcomes Network, London School of Hygiene & Tropical Medicine, London, United-Kingdom


    Mathieu Fauvernier

    Hospices Civils de Lyon-UMR 5558, Université de Lyon, CNRS, France

    Maja Pohar-Perme

    Institute of Biostatistics and Medical Informatics,
    University of Ljubljana, Slovenia


    Roch Giorgi

    SESSTIM, UMR 1252, ISSPAM, Inserm/IRD/Aix-Marseille Université, France

    Bernard Rachet

    Inequalities in Cancer Outcomes Network, London School of Hygiene & Tropical Medicine, London, United-Kingdom


    Juste Goungounga

    Registre Bourguignon des Cancers Digestifs, CHU de Dijon, EPICAD Team, INSERM 1231, Dijon, France

    Laurent Remontet

    Hospices Civils de Lyon-UMR 5558, Université de Lyon,
    CNRS, France


    Michel Grzebyk

    Départment Épidemiologie en Entreprise, Institut National de Recherche et de Sécurité, Vandoeuvre-lès-Nancy, France

    Laurent Roche

    Hospices Civils de Lyon-UMR 5558, Université de Lyon, CNRS, France


    Zoé Urhy

    Santé Publique France - Hospices Civils de Lyon-UMR 5558,
    Université de Lyon, CNRS, France

    Pascale Grosclaude

    Registre des cancers du Tarn IUCT O - INSERM UMR1027 équipe EQUITY, Toulouse, France



    Who should attend?

    Biostatisticians, statisticians, epidemiologists; researchers and students; working in a registry of cancer, of chronic disease or in any other field relevant to these methodologies and applications.

    International audience.

    The number of participants is limited to 40 persons.

    Course language

    Course will be taught in English. All instruction and course materials will be in English too.

    Computing

    Almost half of the course will be devoted to practical applications. Therefore, the applicants will have the opportunity to apply the methods described in the course using real or simulated data.

    Computing sessions will be organised using R software. These sessions will be the opportunity for participants and for the faculty to bring them together to have exiting knowledge exchange.

    Computers will be provided (Windows). Participants can use our computers or bring their own laptop computers.

    Previous experience of using R software is a pre-requisite.

  • One week of Summer School in Corte

    To acces the completes videos, the slides of videos and the practicals contents please go to this Private page

    Speakers

    Title

    Roch Giorgi Goals, epistemological aspects
    Valérie Jooste Indicators-Interpretation
    Maja Pohar-Perme
    Non-parametric estimators of net survival
    Emmanuelle Dantony
    Zoé Uhry
    Flexible parametric models for excess hazard and introduction to penalized framework. Part 1
    Aurélien Belot
    Laurent Roche
    Mathieu Fauvernier
    Flexible parametric models for excess hazard and introduction to penalized framework. Part 2
    Bernard Rachet
    Edmund-Njeru Njagi
    Handling missing data
    Aurélien Belot
    Hadrien Charvat
    Frailty models
    Roch Giorgi
    Multiple events analysis
    Roch Giorgi
    Juste Goungounga
    Handling expected rates tables (without, with missing information) and extensions to other fields: clinical research
    Guy Hédelin
    Michel Grzebyk
    Handling expected rates tables (without, with missing information) and extensions to other fields: occupational epidemiology
  • Scientific programme committee

    Roch Giorgi (UMR 1252 SESSTIM; France); Pascale Grosclaude (FRANCIM, registre des cancers du Tarn; France); Guy Hédelin (Institut National de Recherche et de Sécurité; France); Bernard Rachet (ICON, London School of Hygiene and Tropical Medicine, Department of Non-communicable Disease Epidemiology; Angleterre); Laurent Remontet (Hospices Civiles de Lyon-UMR 5588, Université de Lyon, CNRS; France); Maja Pohar-Perme (Institute for Biostatistics and Medical Informatics; Slovenie).

    Local organisers

    Roch Giorgi

    SESSTIM, UMR 1252, ISSPAM, Inserm/IRD/Aix-Marseille Université, France


    Nathalie Grafféo

    SESSTIM, UMR 1252, ISSPAM, Inserm/IRD/Aix-Marseille Université, France


    Nicolas Ngo

    SESSTIM, UMR 1252, ISSPAM, Inserm/IRD/Aix-Marseille Université, France


    Lamia Daffri

    SESSTIM, UMR 1252, ISSPAM, Inserm/IRD/Aix-Marseille Université, France
  • Course dinner

    Thursday, July 07th at 8:00 pm

    Information concerning the location of the social dinner will be given soon.

    It will be an opportunity for us to exchange in a convivial environment while tasting local products and listening to Corsican music.

    Social activities

    Corte tourist office

    Corte city hall

    Corsica tourist office

  • Course venue

    The course will be held at the Université de Corse Pascal Paoli, at the campus Grimaldi, in Corte, Corsica, France. Theoretical parts will be in the amphitheatre Jean Nicoli, and practical parts using R software will be in computing rooms.

    Getting to Corsica

    General overview and transports to Corsica

    Getting to Corte

    By train

    Main distances

    Guide to Corte

    Accommodation

    Hotels

    Course participants are responsible for booking their room directly with the hotels. After registering for the course, please book your hotel as soon as possible. Please take note of the terms and conditions of the chosen hotel (especially in case of cancellation).

    Listing of hotels

    Apart hotel

    Accommodation

    However, in order to minimize distances between the location of the course and your accommodation, we recommend to book rooms on the Grimaldi campus. The price is 36,61 euros per person per night. The sheets and towels are provided and the rooms include private bathroom and cooking facilities.

    If you want to book a room there or if you need further informations, please contact Mrs. Aurélie Ciabrini by email (aurelie.ciabrini@crous-corse.fr).

    About Corte

    Corte tourist office

    Corte city hall

    Maps

    Corte, course venue and hotels

    Pictures

    LA RESTONICA

    CALVI

    BASTIA

    MONTAGNES

    BONIFACIO

    NONZA

    ILES SANGUINAIRES

    CALANQUES DE PIANA

  • Registration includes access to the 5 days of the course, morning and afternoon tea breaks, daily lunch breaks on each day and invitation to the course reception on the evening of Thursday 07th July.

    Please note that hotel reservations must be made by participants, since the registration fees exclude travel and accommodation costs.

    Course fees

    Prices in EUR, incl. VAT Early bird, until May 31st 2022 From June 01st 2022*
    Participant** 650 € 750 €
    ISCB Members*** 550 € 650 €
    Course reception**** Free Free
    *

    The deadline for registration is June 15th, 2022

    **

    For the Inserm members, or members of a team labelled by Inserm, training office Inserm “Provence-Alpes-Côte d’Azur et Corse” will take charge of 5 registrations of agents paid by Inserm, on the proposal of the organizer of the Corsican Summer School. Order forms, with a short summary of the interest for this advanced course, must be sent to the attention of the local organisers by email: gestion_admin.u1252@inserm.fr.

    ***

    For the ISCB members asking for the discount, 2022 ISCB membership must be provided. See information on the online registration on how to proceed.

    ****

    The course reception (dinner with Corsican songs) is free of charge but you must register. See below for register.

    Method of payment

    Course reception registration

    Please download the course reception registration form, fill out the form, one for each participant, and then send it by email to Mrs Daffri at: gestion_admin.u1252@inserm.fr, with the subject: “HEAR+STAT 2022”.

    Cancellation reception registration

    • In case of cancellation of participation until May 31st, 2022 the registration fee will be refunded.
    • After June 01st, 2022 there will be no refund whatsoever.
    • Cancellations must be communicated in written form.
  • Photos of one week to Corte, at the end of the course…

    Hearstat 2022 Corte

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