@article{barnes:inserm-03193473, TITLE = {{Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants}}, AUTHOR = {Barnes, Daniel and Rookus, Matti and Mcguffog, Lesley and Leslie, Goska and Mooij, Thea and Dennis, Joe and Mavaddat, Nasim and Adlard, Julian and Ahmed, Munaza and Aittom{\"a}ki, Kristiina and Andrieu, Nadine and Andrulis, Irene and Arnold, Norbert and Arun, Banu and Azzollini, Jacopo and Balma{\~n}a, Judith and Barkardottir, Rosa and Barrowdale, Daniel and Benitez, Javier and Berthet, Pascaline and Bialkowska, Katarzyna and Blanco, Amie and Blok, Marinus and Bonanni, Bernardo and Boonen, Susanne and Borg, {\AA}ke and Bozsik, Aniko and Bradbury, Angela and Brennan, Paul and Brewer, Carole and Brunet, Joan and Buys, Saundra and Cald{\'e}s, Trinidad and Caligo, Maria and Campbell, Ian and Christensen, Lise Lotte and Chung, Wendy and Claes, Kathleen and Colas, Chrystelle and Collonge-Rame, Marie-Agn{\`e}s and Cook, Jackie and Daly, Mary and Davidson, Rosemarie and de La Hoya, Miguel and de Putter, Robin and Delnatte, Capucine and Devilee, Peter and Diez, Orland and Ding, Yuan Chun and Domchek, Susan and Dorfling, Cecilia and Dumont, Martine and Eeles, Ros and Ejlertsen, Bent and Engel, Christoph and Evans, D Gareth and Faivre, Laurence and Foretova, Lenka and Fostira, Florentia and Friedlander, Michael and Friedman, Eitan and Frost, Debra and Ganz, Patricia and Garber, Judy and Gehrig, Andrea and Gerdes, Anne-Marie and Gesta, Paul and Giraud, Sophie and Glendon, Gord and Godwin, Andrew and Goldgar, David and Gonz{\'a}lez-Neira, Anna and Greene, Mark and Gschwantler-Kaulich, Daphne and Hahnen, Eric and Hamann, Ute and Hanson, Helen and Hentschel, Julia and Hogervorst, Frans and Hooning, Maartje and Horvath, Judit and Hu, Chunling and Hulick, Peter and Imyanitov, Evgeny and Isaacs, Claudine and Izatt, Louise and Izquierdo, Angel and Jakubowska, Anna and James, Paul and Janavicius, Ramunas and John, Esther and Joseph, Vijai and Karlan, Beth and Kast, Karin and Koudijs, Marco and Kruse, Torben and Kwong, Ava and Laitman, Yael and Lasset, Christine and Lazaro, Conxi and Lester, Jenny and Lesueur, Fabienne and Liljegren, Annelie and Loud, Jennifer and Lubi{\'n}ski, Jan and Mai, Phuong and Manoukian, Siranoush and Mari, V{\'e}ronique and Mebirouk, Noura and Meijers-Heijboer, Hanne and Meindl, Alfons and Mensenkamp, Arjen and Miller, Austin and Montagna, Marco and Mouret-Fourme, Emmanuelle and Mukherjee, Semanti and Mulligan, Anna Marie and Nathanson, Katherine and Neuhausen, Susan and Nevanlinna, Heli and Niederacher, Dieter and Nielsen, Finn Cilius and Nikitina-Zake, Liene and Nogues, Catherine C. and Olah, Edith and Olopade, Olufunmilayo and Ong, Kai-Ren and O'Shaughnessy-Kirwan, Aoife and Osorio, Ana and Ott, Claus-Eric and Papi, Laura and Park, Sue and Parsons, Michael and Pedersen, Inge Sokilde and Peissel, Bernard and Peixoto, Ana and Peterlongo, Paolo and Pfeiler, Georg and Phillips, Kelly-Anne and Prajzendanc, Karolina and Pujana, Miquel Angel and Radice, Paolo and Ramser, Juliane and Ramus, Susan and Rantala, Johanna and Rennert, Gad and Risch, Harvey and Robson, Mark and R{{\o}}nlund, Karina and Salani, Ritu and Schuster, H{\'e}l{\`e}ne and Senter, Leigha and Shah, Payal and Sharma, Priyanka and Side, Lucy and Singer, Christian and Slavin, Thomas and Soucy, Penny and Southey, Melissa and Spurdle, Amanda and Steinemann, Doris and Steinsnyder, Zoe and Stoppa-Lyonnet, Dominique and Sutter, Christian and Tan, Yen Yen and Teixeira, Manuel and Teo, Soo Hwang and Thull, Darcy and Tischkowitz, Marc and Tognazzo, Silvia and Toland, Amanda and Trainer, Alison and Tung, Nadine and van Engelen, Klaartje and van Rensburg, Elizabeth and Vega, Ana and Vierstraete, Jeroen and Wagner, Gabriel and Walker, Lisa and Wang-Gohrke, Shan and Wappenschmidt, Barbara and Weitzel, Jeffrey and Yadav, Siddhartha and Yang, Xin and Yannoukakos, Drakoulis and Zimbalatti, Dario and Offit, Kenneth and Thomassen, Mads and Couch, Fergus and Schmutzler, Rita and Simard, Jacques and Easton, Douglas and Chenevix-Trench, Georgia and Antoniou, Antonis}, URL = {https://inserm.hal.science/inserm-03193473}, JOURNAL = {{Genetics in Medicine}}, PUBLISHER = {{Nature Publishing Group}}, VOLUME = {22}, NUMBER = {10}, PAGES = {1653-1666}, YEAR = {2020}, MONTH = Oct, DOI = {10.1038/s41436-020-0862-x}, KEYWORDS = {BRCA1/2 ; breast cancer ; ovarian cancer ; PRS ; genetics}, PDF = {https://inserm.hal.science/inserm-03193473/file/s41436-020-0862-x.pdf}, HAL_ID = {inserm-03193473}, HAL_VERSION = {v1}, }