@article{cabarrou:inserm-02089323, TITLE = {{Designing phase II clinical trials to target subgroup of interest in a heterogeneous population: A case study using an R package}}, AUTHOR = {Cabarrou, Bastien and Sfumato, Patrick and Leconte, Eve and Boher, Jean-Marie and Filleron, Thomas}, URL = {https://inserm.hal.science/inserm-02089323}, JOURNAL = {{Computers in Biology and Medicine}}, PUBLISHER = {{Elsevier}}, VOLUME = {100}, PAGES = {239-246}, YEAR = {2018}, MONTH = Sep, DOI = {10.1016/j.compbiomed.2018.06.034}, KEYWORDS = {Heterogeneity ; Phase II clinical trial ; R package ; Simon two-stage design ; Single-arm ; Stratified adaptive design ; Target subgroup}, PDF = {https://inserm.hal.science/inserm-02089323v1/file/1-s2.0-S0010482518301823-main.pdf}, HAL_ID = {inserm-02089323}, HAL_VERSION = {v1}, }