@article{caputo:hal-03375857, TITLE = {{Classification of 101 BRCA1 and BRCA2 variants of uncertain significance by cosegregation study: A powerful approach}}, AUTHOR = {Caputo, Sandrine and Golmard, Lisa and L{\'e}one, M{\'e}lanie and Damiola, Francesca and Guillaud-Bataille, Marine and Revillion, Fran{\c c}oise and Rouleau, Etienne and Derive, Nicolas and Buisson, Adrien and Basset, No{\'e}mie and Schwartz, Mathias and Vilquin, Paul and Garrec, Celine and Privat, Maud and Gay-Bellile, Mathilde and Abadie, Caroline and Abidallah, Khadija and Airaud, Fabrice and Allary, Anne-Sophie and Barouk-Simonet, Emmanuelle and Belotti, Muriel and Benigni, Charlotte and Benusiglio, Patrick and Berthemin, Christelle and Berthet, Pascaline and Bertrand, Ophelie and B{\'e}zieau, St{\'e}phane and Bidart, Marie and Bignon, Yves-Jean and Birot, Anne-Marie and Blanluet, Maud and Bloucard, Amelie and Bombled, Johny and Bonadona, Valerie and Bonnet, Fran{\c c}oise and Bonnet-Dupeyron, Marie-No{\"e}lle and Boulaire, Manon and Boulouard, Flavie and Bouras, Ahmed and Bourdon, Violaine and Brahimi, Afane and Brayotel, Fanny and Bressac de Paillerets, Brigitte and Bronnec, No{\'e}mie and Bubien, Virginie and Buecher, Bruno and Cabaret, Odile and Carriere, Jennifer and Chiesa, Jean and Chieze-Val{\'e}ro, Stephanie and Cohen, Camille and Cohen-Haguenauer, Odile and Colas, Chrystelle and Collonge-Rame, Marie-Agn{\`e}s and Conoy, Anne-Laure and Coulet, Florence and Coupier, Isabelle and Crivelli, Louise and Cusin, V{\'e}ronica and de Pauw, Antoine and Dehainault, Catherine and Delhomelle, H{\'e}l{\`e}ne and Delnatte, Capucine and Demontety, Sophie and Denizeau, Philippe and Devulder, Pierre and Dreyfus, Helene and D'enghein, Catherine Dubois and Dupr{\'e}, Ana{\"i}s and Durlach, Anne and Dussart, Sophie and Fajac, Anne and Fekairi, Samira and Fert-Ferrer, Sandra and Fi{\'e}vet, Alice and Fouillet, Robin and Mouret-Fourme, Emmanuelle and Gauthier-Villars, Marion and Gesta, Paul and Giraud, Sophie and Gladieff, Laurence and Goldbarg, Veronica and Goussot, Vincent and Guibert, Virginie and Guillerm, Erell and Guy, Christophe and Hardouin, Agn{\`e}s and Heude, C{\'e}line and Houdayer, Claude and Ingster, Olivier and Jacquot-Sawka, Caroline and Jones, Natalie and Krieger, Sophie and Lacoste, Sofiane and Lallaoui, Hakima and Larbre, Helene and Laug{\'e}, Anthony and Le Guyadec, Gabrielle and Le Mentec, Marine and Lecerf, Caroline and Le Gall, Jessica and Legendre, B{\'e}reng{\`e}re and Legrand, Cl{\'e}mentine and Legros, Ang{\'e}lina and Lejeune, Sophie and Lidereau, Rosette and Lignon, Norbert and Limacher, Jean-Marc and Lizard, Sarab and Longy, Michel and Lortholary, Alain and Macquere, Pierre and Mailliez, Audrey and Malsa, Sarah and Margot, Henri and Mari, V{\'e}ronique and Maugard, Christine and Meira, Cindy and Menjard, Julie and Moli{\`e}re, Diane and Moncoutier, Virginie and Moretta-Serra, Jessica and Muller, Etienne and Nevi{\`e}re, Zoe and Nguyen Minh Tuan, Thien-Vu and Noguchi, Tetsuro and Nogu{\`e}s, Catherine and Oca, Florine and Popovici, Cornel and Prieur, Fabienne and Raad, Sabine and Rey, Jean-Marc and Ricou, Agathe and Salle, Lucie and Saule, Claire and Sevenet, Nicolas and Simaga, Fatoumata and Sobol, Hagay and Suybeng, Voreak and Tennevet, Isabelle and Tenreiro, Henrique and Tinat, Julie and Toulas, Christine and Turbiez, Isabelle and Uhrhammer, Nancy and Vande Perre, Pierre and Vaur, Dominique and Venat, Laurence and Viellard, Nicolas and Villy, Marie-Charlotte and Warcoin, Mathilde and Yvard, Alice and Zattara, Helene and Caron, Olivier and Lasset, Christine and Remenieras, Audrey and Boutry-Kryza, Nadia and Cast{\'e}ra, Laurent and Stoppa-Lyonnet, Dominique}, URL = {https://hal.univ-reims.fr/hal-03375857}, JOURNAL = {{American Journal of Human Genetics}}, PUBLISHER = {{Elsevier (Cell Press)}}, VOLUME = {108}, NUMBER = {10}, PAGES = {1907-1923}, YEAR = {2021}, MONTH = Oct, DOI = {10.1016/j.ajhg.2021.09.003}, PDF = {https://hal.univ-reims.fr/hal-03375857/file/S0002929721003396.pdf}, HAL_ID = {hal-03375857}, HAL_VERSION = {v1}, }