@article{bonadona:hal-00780536, TITLE = {{Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.}}, AUTHOR = {Bonadona, Val{\'e}rie and Bona{\"i}ti, Bernard and Olschwang, Sylviane and Grandjouan, Sophie and Huiart, Laetitia and Longy, Michel and Guimbaud, Rosine and Buecher, Bruno and Bignon, Yves-Jean and Caron, Olivier and Colas, Chrystelle and Nogu{\`e}s, Catherine and Lejeune-Dumoulin, Sophie and Olivier-Faivre, Laurence and Polycarpe-Osaer, Florence and Nguyen, Tan Dat and Desseigne, Fran{\c c}oise and Saurin, Jean-Christophe and Berthet, Pascaline and Leroux, Dominique and Duffour, Jacqueline and Manouvrier, Sylvie and Fr{\'e}bourg, Thierry and Sobol, Hagay and Lasset, Christine and Bona{\"i}ti-Pelli{\'e}, Catherine}, URL = {https://hal.science/hal-00780536}, JOURNAL = {{Journal of the American Medical Association}}, PUBLISHER = {{American Medical Association (AMA)}}, VOLUME = {305}, NUMBER = {22}, PAGES = {2304-2310}, YEAR = {2011}, MONTH = Jun, DOI = {10.1001/jama.2011.743}, KEYWORDS = {NONPOLYPOSIS COLORECTAL-CANCER ; CUMULATIVE LIFETIME INCIDENCE ; AGE-OF-ONSET ; ESTIMATING PENETRANCE ; ENDOMETRIAL CANCER ; PROVEN MUTATIONS ; GRL METHOD ; CARRIERS ; HNPCC ; 121 FAMILIES}, HAL_ID = {hal-00780536}, HAL_VERSION = {v1}, }